Identification of Oxalic Acid and Tartaric Acid as Major Persistent Pain-inducing Toxins in the Stinging Hairs of the Nettle, Urtica thunbergiana | Zendy

HAN YI FU | Zendy; Shiang Jiuun Chen | Zendy; RueiFeng Chen | Zendy; Ding Wang | Zendy; LING LONG KUO-HUANG | Zendy; Rong Huang | Zendy

Open Access

Identification of Oxalic Acid and Tartaric Acid as Major Persistent Pain-inducing Toxins in the Stinging Hairs of the Nettle, Urtica thunbergiana

Author(s) -

HAN YI FU,

Shiang Jiuun Chen,

RueiFeng Chen,

Ding Wang,

LING LONG KUO-HUANG,

Rong Huang

Publication year - 2006

Publication title -

annals of botany

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.567

H-Index - 176

eISSN - 1095-8290

pISSN - 0305-7364

DOI - 10.1093/aob/mcl089

Subject(s) - tartaric acid , histamine , oxalic acid , formic acid , biology , high performance liquid chromatography , serotonin , chromatography , botany , biochemistry , chemistry , citric acid , pharmacology , receptor

Once human skin contacts stinging hairs of Urtica spp. (stinging nettles), the irritant is released and produces pain, wheals or a stinging sensation which may last for >12 h. However, the existence of pain-inducing toxins in the stinging hairs of Urtica thunbergiana has never been systematically demonstrated. Experiments were therefore conducted to identify the persistent pain-inducing agents in the stinging hairs of U. thunbergiana.

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