Biomonitoring Hexamethylene Diisocyanate (HDI) Exposure Based on Serum Levels of HDI-Specific IgG
Author(s) -
Adam V. Wisnewski,
Meredith H. Stowe,
Abby L. Nerlinger,
Paul Opare-addo,
David DeCamp,
Christopher R. Kleinsmith,
Carrie A. Redlich
Publication year - 2012
Publication title -
the annals of occupational hygiene
Language(s) - English
Resource type - Journals
eISSN - 1475-3162
pISSN - 0003-4878
DOI - 10.1093/annhyg/mes024
Subject(s) - hexamethylene diisocyanate , biomonitoring , occupational exposure , immunology , chemistry , toxicology , medicine , polyurethane , environmental health , biology , environmental chemistry , organic chemistry
Isocyanate chemicals essential for polyurethane production are widely used industrially, and are increasingly found in consumer products. Asthma and other adverse health effects of isocyanates are well-documented and exposure surveillance is crucial to disease prevention. Hexamethylene diisocyanate (HDI)-specific serum immunoglobulin G (IgG) was evaluated as an exposure biomarker among workers at a US Air Force Air Logistics Center, which includes a large aircraft maintenance facility.
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