Effects of Moderate Ethanol Consumption on Lipid Metabolism and Inflammation Through Regulation of Gene Expression in Rats
Author(s) -
Meegan Justice,
Autumn Ferrugia,
Joshua Beidler,
Jerrold C. Penprase,
Patricia Cintora,
Danielle Erwin,
Octavio Medrano,
Susan M. Brasser,
Mee Young Hong
Publication year - 2018
Publication title -
alcohol and alcoholism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.747
H-Index - 99
eISSN - 1464-3502
pISSN - 0735-0414
DOI - 10.1093/alcalc/agy079
Subject(s) - endocrinology , medicine , ethanol , cholesterol , downregulation and upregulation , paraoxonase , sterol regulatory element binding protein , chemistry , low density lipoprotein , inflammation , lipoprotein , alcohol , lipid metabolism , sterol , biochemistry , oxidative stress , gene
Epidemiological studies and experimental data from rodent models have reported a non-linear relationship between consumption of alcohol and cardiovascular disease (CVD) risk that suggests that light-to-moderate drinking as opposed to excessive consumption may provide some cardiovascular benefits. The present study examined potential mechanisms by which moderate alcohol consumption may provide a protective effect against CVD.
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