Open AccessPrazosin Prevents Increased Anxiety Behavior That Occurs in Response to Stress During Alcohol Deprivations
Author(s) -
Dennis D. Rasmussen,
Carrie Kincaid,
Janice C. Froehlich
Publication year - 2016
Publication title -
alcohol and alcoholism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.747
H-Index - 99
eISSN - 1464-3502
pISSN - 0735-0414
DOI - 10.1093/alcalc/agw082
Subject(s) - prazosin , anxiety , alcohol , alcohol dependence , psychology , medicine , elevated plus maze , abstinence , endocrinology , antagonist , psychiatry , receptor , chemistry , biochemistry
Stress-induced anxiety is a risk factor for relapse to alcohol drinking. The aim of this study was to test the hypothesis that the central nervous system (CNS)-active α 1 -adrenergic receptor antagonist, prazosin, would block the stress-induced increase in anxiety that occurs during alcohol deprivations.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom