Open AccessMechanisms of Neurodegeneration and Regeneration in Alcoholism
Author(s) -
Fulton T. Crews,
Kimberly Nixon
Publication year - 2008
Publication title -
alcohol and alcoholism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.747
H-Index - 99
eISSN - 1464-3502
pISSN - 0735-0414
DOI - 10.1093/alcalc/agn079
Subject(s) - neurodegeneration , proinflammatory cytokine , creb , neurogenesis , neuroprotection , oxidative stress , neuroscience , binge drinking , neurotoxicity , medicine , biology , endocrinology , inflammation , transcription factor , poison control , toxicity , biochemistry , disease , environmental health , suicide prevention , gene
This is a review of preclinical studies covering alcohol-induced brain neuronal death and loss of neurogenesis as well as abstinence-induced brain cell genesis, e.g. brain regeneration. Efforts are made to relate preclinical studies to human studies.
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