Clinical approach to intestinal maturation in neonates prenatally exposed to alcohol | Zendy

Carmen Través | Zendy; O. Coll | Zendy; V. Cararach | Zendy; Antoni Gual | Zendy; Begoña Martínez de Tejada | Zendy; M. Dolores LópezTejero | Zendy

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Clinical approach to intestinal maturation in neonates prenatally exposed to alcohol

Author(s) -

Carmen Través,

O. Coll,

V. Cararach,

Antoni Gual,

Begoña Martínez de Tejada,

M. Dolores LópezTejero

Publication year - 2007

Publication title -

alcohol and alcoholism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.747

H-Index - 99

eISSN - 1464-3502

pISSN - 0735-0414

DOI - 10.1093/alcalc/agm005

Subject(s) - in utero , fetus , gestation , pregnancy , umbilical cord , gestational age , medicine , apolipoprotein b , amniotic fluid , physiology , fetal alcohol syndrome , gastroenterology , endocrinology , obstetrics , biology , immunology , cholesterol , genetics

The need for a non-invasive diagnosis of the effects of ethanol in utero on the development of the intestine in humans led us to look for a serum marker of the structural integrity of the intestine. We propose apolipoprotein A-IV (apoA-IV) as a possible candidate. In humans this protein is synthesized only by intestinal mucosa, it is expressed in the enterocyte of the foetus from 20 weeks of gestation, and it is released to the blood stream after synthesis.

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