ARGININE CHALLENGE UNRAVELS PERSISTENT DISTURBANCES OF UREA CYCLE AND GLUCONEOGENESIS IN ABSTINENT ALCOHOLICS
Author(s) -
Martin Hasselblatt,
Henning Krampe,
Silke Jacobs,
HEIKE SINDRAM,
Victor W. Armstrong,
Markus Hecker,
Hannelore Ehrenreich
Publication year - 2006
Publication title -
alcohol and alcoholism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.747
H-Index - 99
eISSN - 1464-3502
pISSN - 0735-0414
DOI - 10.1093/alcalc/agl032
Subject(s) - medicine , urea cycle , arginine , ornithine , endocrinology , urea , gluconeogenesis , citrulline , glucagon , arginase , glutamine , hormone , chemistry , metabolism , biochemistry , amino acid
Data on recovery from hormonal and metabolic sequelae of alcoholism in strictly controlled alcohol abstinence are mainly restricted to short-term abstention. Our previous findings of persistently decreased plasma and urinary urea concentrations in long-term abstinent alcoholics prompted us to further elucidate this unexplained phenomenon.
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