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Some models of chronic ethanol administration resulted in decreased proteasome activities. The mechanisms still remain speculative. In the present study, we tested another model of alcoholization with high blood alcohol levels (BALs) and high acetaldehyde fluxes as well as the in vitro effect of acetaldehyde on proteasome. Methods/

alcohol and alcoholism

THE EFFECTS OF ACETALDEHYDE IN VITRO ON PROTEASOME ACTIVITIES AND ITS POTENTIAL INVOLVEMENT AFTER ALCOHOLIZATION OF RATS BY INHALATION OF ETHANOL VAPOURS