Open AccessHISTONE H3 MODIFICATIONS IN RAT HEPATIC STELLATE CELLS BY ETHANOL
Author(s) -
JEE-SOO KIM,
Shivendra D. Shukla
Publication year - 2005
Publication title -
alcohol and alcoholism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.747
H-Index - 99
eISSN - 1464-3502
pISSN - 0735-0414
DOI - 10.1093/alcalc/agh170
Subject(s) - hepatic stellate cell , histone h3 , ethanol , chemistry , histone , medicine , biochemistry , gene
Hepatic stellate cells (HSCs) play critical roles in the development of hepatic fibrosis caused by various agents including alcohol. Ethanol causes post-translational modification in histone. The goal of this study is to investigate whether ethanol affected acetylation and methylation of histone H3 in rat HSCs.
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