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CHRONIC CONSUMPTION OF ETHANOL LEADS TO SUBSTANTIAL CELL DAMAGE IN CULTURED RAT ASTROCYTES IN CONDITIONS PROMOTING ACETALDEHYDE ACCUMULATION
Author(s) -
Nathalie Signorini-Allibe,
B. Gonthier,
Frédéric Lamarche,
Hélène Eysseric,
Luc Barret
Publication year - 2005
Publication title -
alcohol and alcoholism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.747
H-Index - 99
eISSN - 1464-3502
pISSN - 0735-0414
DOI - 10.1093/alcalc/agh097
Subject(s) - acetaldehyde , ethanol , astrocyte , chronic alcoholism , chemistry , medicine , endocrinology , biochemistry , biology , central nervous system
This study aimed at comparing the cerebral cytotoxicity of ethanol and its main metabolite acetaldehyde after acute or chronic exposures of rat astrocytes in primary culture.

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