ROLE OF ANGIOTENSIN II AND THE SUBFORNICAL ORGAN IN THE PHARMACOLOGICAL ACTIONS OF ETHANOL
Author(s) -
Justin L. Grobe,
Neil E. Rowland,
Michael J. Katovich
Publication year - 2004
Publication title -
alcohol and alcoholism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.747
H-Index - 99
eISSN - 1464-3502
pISSN - 0735-0414
DOI - 10.1093/alcalc/agh079
Subject(s) - subfornical organ , angiotensin ii , ethanol , medicine , endocrinology , pharmacology , chemistry , receptor , biochemistry
The current study was designed to evaluate if angiotensin II mediates the hypothermic effects of ethanol, and to determine if the effects of angiotensin are mediated centrally. We also tested the hypothesis that the subfornical organ (SFO) is a site responsible for the alterations in body temperature and aerial righting reflex mediated by ethanol and for the modulation of ethanol consumption in rats.
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