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We have investigated proopiomelanocortin (POMC) and neuropeptide Y (NPY) gene expression in the arcuate nucleus of the hypothalamus comparing high alcohol preference (HAP) rats and low alcohol preference (LAP) rats under basal conditions using in situ hybridization histochemistry.

alcohol and alcoholism

HIGH ALCOHOL PREFERRING (HAP) AND LOW ALCOHOL PREFERRING (LAP) RATS SHOW ALTERED PROOPIOMELANOCORTIN (POMC) MESSENGER RNA EXPRESSION IN THE ARCUATE NUCLEUS