DIFFERENCES IN BRAIN FUNCTION BETWEEN RELAPSING AND ABSTAINING ALCOHOL-DEPENDENT PATIENTS, EVALUATED BY EEG MAPPING
Author(s) -
G. SaletuZyhlarz
Publication year - 2004
Publication title -
alcohol and alcoholism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.747
H-Index - 99
eISSN - 1464-3502
pISSN - 0735-0414
DOI - 10.1093/alcalc/agh041
Subject(s) - electroencephalography , placebo , alpha (finance) , medicine , vigilance (psychology) , psychology , anesthesia , psychiatry , surgery , neuroscience , construct validity , alternative medicine , pathology , patient satisfaction
Early clinical electroencephalographers reported that low-voltage fast desynchronized patterns were frequently seen in chronic alcoholism, suggesting hyperarousal of the central nervous system (CNS). The aim of the present study was to investigate the brain function of drug-free, detoxified alcoholics, and compare this with that of normal controls, utilizing computerized quantitative EEG analysis and subsequent EEG mapping. Moreover, differences between patients relapsing or abstaining during 6 months of relapse prevention therapy, pharmacologically supported by either flupentixol decanoate 10 mg or placebo i.m. every 2 weeks, were determined.
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