RELATIONSHIP BETWEEN ETHANOL-INDUCED CHANGES IN BRAIN REGIONAL METABOLISM AND ITS MOTOR, BEHAVIOURAL AND COGNITIVE EFFECTS | Zendy

Wei Zhu | Zendy; Nora D. Volkow | Zendy; Yeming Ma | Zendy; Joanna S. Fowler | Zendy; GeneJack Wang | Zendy

Open Access

RELATIONSHIP BETWEEN ETHANOL-INDUCED CHANGES IN BRAIN REGIONAL METABOLISM AND ITS MOTOR, BEHAVIOURAL AND COGNITIVE EFFECTS

Author(s) -

Wei Zhu,

Nora D. Volkow,

Yeming Ma,

Joanna S. Fowler,

GeneJack Wang

Publication year - 2003

Publication title -

alcohol and alcoholism

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.747

H-Index - 99

eISSN - 1464-3502

pISSN - 0735-0414

DOI - 10.1093/alcalc/agh023

Subject(s) - basal ganglia , insula , psychology , cerebellum , cognition , neuroscience , effects of sleep deprivation on cognitive performance , endocrinology , central nervous system , medicine

Acute alcohol administration induces marked decreases in glucose metabolism throughout the human brain. However, the relationship between alcohol's effects on brain metabolism and the behavioural changes that occur with intoxication are still unclear. Here we assessed this association using principal component analysis for dimension reduction and canonical correlations to gauge inter-class relationships. We also used canonical correlations in the polynomial space to assess for possible nonlinear relationships.

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