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SERTRALINE FOR THE PREVENTION OF RELAPSE IN DETOXICATED ALCOHOL DEPENDENT PATIENTS WITH A COMORBID DEPRESSIVE DISORDER: A RANDOMIZED CONTROLLED TRIAL
Author(s) -
Antoni Gual
Publication year - 2003
Publication title -
alcohol and alcoholism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.747
H-Index - 99
eISSN - 1464-3502
pISSN - 0735-0414
DOI - 10.1093/alcalc/agg124
Subject(s) - sertraline , placebo , randomized controlled trial , medicine , depression (economics) , psychology , abstinence , major depressive disorder , psychiatry , adverse effect , alcohol dependence , antidepressant , alcohol , anxiety , alternative medicine , cognition , macroeconomics , pathology , economics , biochemistry , chemistry
We performed a double-blind, placebo-controlled randomized trial of sertraline in recently detoxified alcohol-dependent patients with current depressive symptoms. The objectives of the study were to evaluate the efficacy of sertraline at achieving stable abstinence, at ameliorating depressive symptoms and at improving quality of life in these patients.

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