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The influence of alcohol on the brain serotonergic system has been studied for several decades with some discordant results. The effects of continuous and constant treatment with ethanol on the rates of serotonin [5-hydroxytryptamine (5-HT)] synthesis in discrete regions of the rat brain were studied.

alcohol and alcoholism

CONTINUOUS ETHANOL ADMINISTRATION INFLUENCES RAT BRAIN 5-HYDROXYTRYPTAMINE SYNTHESIS NON-UNIFORMLY: alpha-[14C]METHYL-L-TRYPTOPHAN AUTORADIOGRAPHIC MEASUREMENTS