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NEUTROPHIL ACTIVATION BY MURINE RETROVIRAL INFECTION DURING CHRONIC ETHANOL CONSUMPTION
Author(s) -
Yinhong Chen,
Sam Mendoza,
Grace DavisGorman,
Zoë Cohen,
Raoul Gonzales,
Hillary A. Tuttle,
Paul F. McDonagh,
Ronald R. Watson
Publication year - 2003
Publication title -
alcohol and alcoholism
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.747
H-Index - 99
eISSN - 1464-3502
pISSN - 0735-0414
DOI - 10.1093/alcalc/agg049
Subject(s) - integrin alpha m , retrovirus , flow cytometry , immunology , ethanol , reactive oxygen species , neutrophile , granulocyte , biology , medicine , inflammation , virus , biochemistry
Neutrophil adhesion molecule CD11b and reactive oxygen species (ROS) are neutrophil activation markers for evaluating the functional activity of neutrophils. The aim of this study was to determine if neutrophils are activated in murine AIDS and/or chronic ethanol consumption and if neutrophil CD11b expression and ROS production vary when progressive retrovirus infection occurs.

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