Pitavastatin Upregulates Nitric Oxide Synthases in the Kidney of Spontaneously Hypertensive Rats and Wistar–Kyoto Rats | Zendy

Gaizun Hu | Zendy; Osamu Ito | Zendy; Rong Rong | Zendy; Akihiro Sakuyama | Zendy; Takahiro Miura | Zendy; Daisuke Ito | Zendy; Yoshiko Ogawa | Zendy; Masahiro Kohzuki | Zendy

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Pitavastatin Upregulates Nitric Oxide Synthases in the Kidney of Spontaneously Hypertensive Rats and Wistar–Kyoto Rats

Author(s) -

Gaizun Hu,

Osamu Ito,

Rong Rong,

Akihiro Sakuyama,

Takahiro Miura,

Daisuke Ito,

Yoshiko Ogawa,

Masahiro Kohzuki

Publication year - 2018

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1093/ajh/hpy098

Subject(s) - enos , medicine , endocrinology , endothelial nos , nitric oxide synthase , excretion , kidney , nitric oxide , nitric oxide synthase type iii , blood pressure

Clinical trials show potent renoprotective effects of pitavastatin (PTV), although the precise mechanism for these renoprotective effects is not fully clarified. The aim of this study was to examine the antihypertensive and renoprotective effects of PTV, focusing on the nitric oxide (NO) system.

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