MicroRNAs in Peripheral Mononuclear Cells as Potential Biomarkers in Hypertensive Patients With Heart Failure With Preserved Ejection Fraction | Zendy

Maria Marketou | Zendy; Joanna Kontaraki | Zendy; Spyros Maragkoudakis | Zendy; Alexandros Patrianakos | Zendy; J. Konstantinou | Zendy; H. Nakou | Zendy; D. Vougia | Zendy; J. Logakis | Zendy; Gregory Chlouverakis | Zendy; Panos E. Vardas | Zendy; Fragiskos Parthenakis | Zendy

Open Access

MicroRNAs in Peripheral Mononuclear Cells as Potential Biomarkers in Hypertensive Patients With Heart Failure With Preserved Ejection Fraction

Author(s) -

Maria Marketou,

Joanna Kontaraki,

Spyros Maragkoudakis,

Alexandros Patrianakos,

J. Konstantinou,

H. Nakou,

D. Vougia,

J. Logakis,

Gregory Chlouverakis,

Panos E. Vardas,

Fragiskos Parthenakis

Publication year - 2018

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1093/ajh/hpy035

Subject(s) - medicine , ejection fraction , peripheral blood mononuclear cell , cardiology , heart failure with preserved ejection fraction , heart failure , microrna , peripheral , gene , biochemistry , chemistry , in vitro

MicroRNAs (miRs) regulate gene expression and play an important role in ventricular and vascular remodeling. However, there are limited data regarding their role in heart failure with preserved ejection fraction (HFpEF). The aim of this study was to assess gene expression of miR-1, miR-133a, miR-21, miR-208b, miR-499, and miR-26b in peripheral blood mononuclear cells (PBMCs) in hypertensive patients with HFpEF and to evaluate their association with their exercise capacity.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research