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Total and Fetal Circulating Cell-Free DNA, Angiogenic, and Antiangiogenic Factors in Preeclampsia and HELLP Syndrome
Author(s) -
Rocío MúñozHernández,
Pablo MedranoCampillo,
María Luisa Miranda,
Hada C. Macher,
Juan Manuel PraenaFernández,
Antonio J. VallejoVaz,
María J. Dominguez-Simeon,
Rafael MorenoLuna,
Pablo Stiefel
Publication year - 2017
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1093/ajh/hpx024
Subject(s) - hellp syndrome , medicine , preeclampsia , placental growth factor , proteinuria , endoglin , gastroenterology , receiver operating characteristic , cell free fetal dna , soluble fms like tyrosine kinase 1 , fetus , pregnancy , endocrinology , vascular endothelial growth factor , prenatal diagnosis , genetics , stem cell , cd34 , vegf receptors , biology , kidney
Preeclampsia (PE) is a hypertensive disorder of pregnancy characterized by hypertension and proteinuria. The HELLP syndrome is the most severe form of PE. The aim of the present study was to determine different potential biomarkers that may help us perform an early diagnosis of the disease, assess on the severity of the disease, and/or predict maternal or fetal adverse outcomes.

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