Associations of Renin–Angiotensin–Aldosterone System Genes With Blood Pressure Changes and Hypertension Incidence
Author(s) -
William He,
Changwei Li,
D. C. Rao,
James E. Hixson,
Jianfeng Huang,
Jie Cao,
Treva Rice,
Lawrence C. Shimmin,
Dongfeng Gu,
Tanika N. Kelly
Publication year - 2015
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1093/ajh/hpv033
Subject(s) - medicine , blood pressure , single nucleotide polymorphism , longitudinal study , cardiology , diastole , population , genetic epidemiology , systolic hypertension , renin–angiotensin system , endocrinology , epidemiology , gene , genetics , genotype , biology , pathology , environmental health
The renin-angiotensin-aldosterone system (RAAS) plays an important role in blood pressure (BP) regulation. The current study uses single-marker and gene-based analyses to examine the association between RAAS genes and longitudinal BP phenotypes in a Han Chinese population.
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