Open AccessEffects of Low-Dose Atorvastatin on Arterial Stiffness and Central Aortic Pressure Augmentation in Patients With Hypertension and Hypercholesterolemia
Author(s) -
Angeliki Kanaki,
Pantelis Sarafidis,
Panagiotis I. Georgianos,
K. Kanavos,
I. Tziolas,
Pantelis Zebekakis,
Anastasios N. Lasaridis
Publication year - 2013
Publication title -
american journal of hypertension
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.009
H-Index - 136
eISSN - 1941-7225
pISSN - 0895-7061
DOI - 10.1093/ajh/hps098
Subject(s) - medicine , atorvastatin , arterial stiffness , cardiology , aortic pressure , blood pressure , pulse wave velocity
Experimental and clinical data suggest that statins exert anti-inflammatory and antiproliferative actions on vasculature beyond their lipid-lowering properties. Whether these pleiotropic effects of statins translate into a beneficial effect on arterial stiffness is not clear. This study aimed to evaluate the potential effects of low-dose atorvastatin treatment on arterial stiffness and central arterial pressure waveforms in patients with mild hypertension and hypercholesterolemia.
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