Interleukin-12 Is Associated With Arterial Stiffness in Healthy Individuals | Zendy

Kenneth Yong | Zendy; Gursharan Dogra | Zendy; Neil Boudville | Zendy; Doris Chan | Zendy; Leon A. Adams | Zendy; H. Ching | Zendy; Ee Mun Lim | Zendy; Wai H. Lim | Zendy

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Interleukin-12 Is Associated With Arterial Stiffness in Healthy Individuals

Author(s) -

Kenneth Yong,

Gursharan Dogra,

Neil Boudville,

Doris Chan,

Leon A. Adams,

H. Ching,

Ee Mun Lim,

Wai H. Lim

Publication year - 2012

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1093/ajh/hps032

Subject(s) - medicine , arterial stiffness , pulse wave velocity , blood pressure , proinflammatory cytokine , cardiology , pulse pressure , interleukin 6 , inflammation

Atherosclerotic cardiovascular disease (CVD) is a chronic inflammatory disease mediated by the proinflammatory cytokines interleukin-12 (IL-12) and interleukin-18 (IL-18). Evidence suggests that IL-12 is dominant in early atherosclerosis, while IL-18 is critical in advanced atherosclerosis. In this study, we explore the association between IL-12 and IL-18 and arterial stiffness in healthy individuals.

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