Folate Deficiency Is Associated With Oxidative Stress, Increased Blood Pressure, and Insulin Resistance in Spontaneously Hypertensive Rats | Zendy

Michal Pravenec | Zendy; Viktor Kožich | Zendy; Jakub Krijt | Zendy; Jitka Sokolová | Zendy; Václav Zı́dek | Zendy; V. Landa | Zendy; Miroslava Šimáková | Zendy; Petr Mlejnek | Zendy; Jan Šilhavý | Zendy; Olena Oliyarnyk | Zendy; L Kazdová | Zendy; Theodore W. Kurtz | Zendy

Open Access

Folate Deficiency Is Associated With Oxidative Stress, Increased Blood Pressure, and Insulin Resistance in Spontaneously Hypertensive Rats

Author(s) -

Michal Pravenec,

Viktor Kožich,

Jakub Krijt,

Jitka Sokolová,

Václav Zı́dek,

V. Landa,

Miroslava Šimáková,

Petr Mlejnek,

Jan Šilhavý,

Olena Oliyarnyk,

L Kazdová,

Theodore W. Kurtz

Publication year - 2012

Publication title -

american journal of hypertension

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.009

H-Index - 136

eISSN - 1941-7225

pISSN - 0895-7061

DOI - 10.1093/ajh/hps015

Subject(s) - medicine , endocrinology , hyperhomocysteinemia , oxidative stress , pathogenesis , metabolic syndrome , blood pressure , insulin resistance , homocysteine , diabetes mellitus , hemodynamics

The role of folate deficiency and associated hyperhomocysteinemia in the pathogenesis of metabolic syndrome is not fully established. In the current study, we analyzed the role of folate deficiency in pathogenesis of the metabolic syndrome in the spontaneously hypertensive rat (SHR).

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