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The Rising Relative Risk of Mortality for Singles: Meta-Analysis and Meta-Regression
Author(s) -
David J. Roelfs,
Eran Shor,
Rachel Kalish,
Tamar Yogev
Publication year - 2011
Publication title -
american journal of epidemiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.33
H-Index - 256
eISSN - 1476-6256
pISSN - 0002-9262
DOI - 10.1093/aje/kwr111
Subject(s) - hazard ratio , confidence interval , meta analysis , demography , medicine , relative risk , multivariate statistics , hazard , meta regression , proportional hazards model , statistics , mathematics , chemistry , organic chemistry , sociology
Never-married persons (singles) constitute a growing demographic group; yet, the magnitude of the all-cause relative mortality risk for nonelderly singles is not known and important moderating factors have not been explored. The authors used meta-analysis to examine 641 risk estimates from 95 publications that provided data on more than 500 million persons. The comparison group consisted of currently married individuals. The mean hazard ratio for mortality was 1.24 (95% confidence interval: 1.19, 1.30) among multivariate-adjusted hazard ratios with a high subjective quality rating. Meta-regressions showed that hazard ratios have been modestly increasing over time for both genders, but have done so somewhat more rapidly for women. The results also showed that the hazard ratio decreased with age and that study quality has an important relation to hazard ratio magnitude.

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