RE: “WHY EVIDENCE FOR THE FETAL ORIGINS OF ADULT DISEASE MIGHT BE A STATISTICAL ARTIFACT: THE ‘REVERSAL PARADOX’ FOR THE RELATION BETWEEN BIRTH WEIGHT AND BLOOD PRESSURE IN LATER LIFE” | Zendy

Tim Cole | Zendy

Open Access

RE: “WHY EVIDENCE FOR THE FETAL ORIGINS OF ADULT DISEASE MIGHT BE A STATISTICAL ARTIFACT: THE ‘REVERSAL PARADOX’ FOR THE RELATION BETWEEN BIRTH WEIGHT AND BLOOD PRESSURE IN LATER LIFE”

Author(s) -

Tim Cole

Publication year - 2005

Publication title -

american journal of epidemiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.33

H-Index - 256

eISSN - 1476-6256

pISSN - 0002-9262

DOI - 10.1093/aje/kwi231

Subject(s) - artifact (error) , relation (database) , blood pressure , disease , medicine , fetus , birth weight , demography , pregnancy , psychology , biology , neuroscience , sociology , genetics , database , computer science

Assume that the correlations of birth weight and current weight with blood pressure are r1 and r2 respectively, while the birth weight vs current weight correlation is r12 . In the z-score regression of blood pressure on birth weight, the unadjusted birth weight coefficient is equal to the correlation r1 , while adjusted for current weight the birth weight coefficient is 1 (r1 r2r12 ) / (1 r12 2 ) .

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