n–3 Fatty acid erythrocyte membrane content, APOE ε4, and cognitive variation: an observational follow-up study in late adulthood
Author(s) -
Lawrence J. Whalley,
Ian J. Deary,
John M. Starr,
Klaus W.J. Wahle,
K. A. Rance,
Victoria J. Bourne,
Helen Fox
Publication year - 2008
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.1093/ajcn/87.2.449
Subject(s) - polyunsaturated fatty acid , apolipoprotein e , allele , cognition , genotype , effects of sleep deprivation on cognitive performance , psychology , cognitive decline , medicine , endocrinology , biology , fatty acid , genetics , biochemistry , gene , psychiatry , dementia , disease
Evidence for an inverse relation between dietary intake of n-3 polyunsaturated fatty acids (PUFAs) and age-related cognitive decline is inconsistent. This inconsistency may arise because the relation is present only in the absence of the apolipoprotein E epsilon4 (APOE epsilon4) allele.
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom