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Randomized controlled trial of the effect of selenium supplementation on thyroid function in the elderly in the United Kingdom
Author(s) -
Margaret P. Rayman,
Alex J. Thompson,
Bram Bekaert,
Janet Catterick,
Rachel Galassini,
Emma Hall,
Margaret Warren-Perry,
Geoffrey J. Beckett
Publication year - 2008
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.1093/ajcn/87.2.370
Subject(s) - selenium , medicine , euthyroid , endocrinology , thyroid function , deiodinase , triiodothyronine , thyroid , thyroid stimulating hormone , placebo , hormone , chemistry , alternative medicine , organic chemistry , pathology
Thyroid function depends on the essential trace mineral selenium, which is at the active center of the iodothyronine deiodinase enzymes that catalyze the conversion of the prohormone thyroxine (T(4)) to the active form of thyroid hormone, triiodothyronine (T(3)).

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