GSTT1 genotype modifies the association between cruciferous vegetable intake and the risk of myocardial infarction | Zendy

Marilyn C. Cornelis | Zendy; Ahmed ElSohemy | Zendy; Hannia Campos | Zendy

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GSTT1 genotype modifies the association between cruciferous vegetable intake and the risk of myocardial infarction

Author(s) -

Marilyn C. Cornelis,

Ahmed ElSohemy,

Hannia Campos

Publication year - 2007

Publication title -

american journal of clinical nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.608

H-Index - 336

eISSN - 1938-3207

pISSN - 0002-9165

DOI - 10.1093/ajcn/86.3.752

Subject(s) - cruciferous vegetables , genotype , medicine , odds ratio , gstp1 , myocardial infarction , sulforaphane , allele , food science , physiology , biology , cancer , genetics , gene , cancer research

Cruciferous vegetables are a major dietary source of isothiocyanates that may protect against coronary heart disease. Isothiocyanates induce glutathione S-transferases (GSTs), polymorphic genes that code for enzymes that conjugate isothiocyanates, as well as mutagens and reactive oxygen species, to make them more readily excretable.

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