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Coffee drinking induces incorporation of phenolic acids into LDL and increases the resistance of LDL to ex vivo oxidation in humans
Author(s) -
Fausta Natella,
Mirella Nardini,
Federica Belelli,
Cristina Scaccini
Publication year - 2007
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.1093/ajcn/86.3.604
Subject(s) - chemistry , caffeic acid , ex vivo , antioxidant , chlorogenic acid , food science , oxidative phosphorylation , ferulic acid , ldl cholesterol , phenolic acid , biochemistry , cholesterol , in vitro
Epidemiologic and intervention studies indicate that both diet as a whole and single dietary components are involved in the risk of atherosclerosis. The resistance of LDL to oxidative modification is an ex vivo indicator of risk, which is modulated by dietary components. Coffee contains phenolic compounds with antioxidant activity. These molecules are found in plasma after the consumption of coffee, and it has been shown that, in vitro, they are able to decrease the susceptibility of LDL to oxidation.

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