Schistosomiasis japonica, anemia, and iron status in children, adolescents, and young adults in Leyte, Philippines
Author(s) -
Tjalling Leenstra,
Luz P. Acosta,
Gretchen Langdon,
Daria L. Manalo,
Li Su,
Remigio M. Olveda,
Stephen T. McGarvey,
Jonathan D. Kurtis,
Jennifer F. Friedman
Publication year - 2006
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.1093/ajcn/83.2.371
Subject(s) - anemia , iron deficiency anemia , medicine , schistosoma japonicum , odds ratio , iron deficiency , hemoglobin , immunology , schistosomiasis , physiology , helminths
Observational and interventional evidence supports a relation between human schistosomiasis and anemia; however, the exact causal mechanisms remain unclear. Eggs translocating across the intestinal or bladder wall may result in extracorporeal blood loss with subsequent iron deficiency. Alternatively, anemia may result from cytokine-mediated dyserythropoiesis, as seen in anemia of inflammation.
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