Mixed tocopherols inhibit platelet aggregation in humans: potential mechanisms | Zendy

Meilin Liu | Zendy; Agneta Wallmon | Zendy; Caroline Olsson-Mortlock | Zendy; Rolf Wallin | Zendy; Tom Saldeen | Zendy

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Mixed tocopherols inhibit platelet aggregation in humans: potential mechanisms

Author(s) -

Meilin Liu,

Agneta Wallmon,

Caroline Olsson-Mortlock,

Rolf Wallin,

Tom Saldeen

Publication year - 2003

Publication title -

american journal of clinical nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.608

H-Index - 336

eISSN - 1938-3207

pISSN - 0002-9165

DOI - 10.1093/ajcn/77.3.700

Subject(s) - chemistry , protein kinase c , tocopherol , platelet , nitric oxide , vitamin e , platelet activation , endocrinology , superoxide dismutase , medicine , biochemistry , pharmacology , antioxidant , kinase , organic chemistry

Epidemiologic studies have shown an inverse correlation between acute coronary events and high intake of dietary vitamin E. Recent clinical studies, however, failed to show any beneficial effects of alpha-tocopherol on cardiovascular events. Absence of tocopherols other than alpha-tocopherol in the clinical studies may account for the conflicting results.

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