Open AccessGeneration of protein adducts with malondialdehyde and acetaldehyde in muscles with predominantly type I or type II fibers in rats exposed to ethanol and the acetaldehyde dehydrogenase inhibitor cyanamide
Author(s) -
Onni Niemelä,
Seppo Parkkila,
Michael Koll,
Victor R. Preedy
Publication year - 2002
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.1093/ajcn/76.3.668
Subject(s) - acetaldehyde , malondialdehyde , cyanamide , chemistry , alcohol dehydrogenase , aldehyde dehydrogenase , biochemistry , ethanol , endocrinology , medicine , antioxidant , enzyme
Alcoholic myopathy is known to primarily affect type II muscle fibers (glycolytic, fast-twitch, anaerobic), whereas type I fibers (oxidative, slow-twitch, aerobic) are relatively protected.
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