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Effects of vitamin C and vitamin E on in vivo lipid peroxidation: results of a randomized controlled trial
Author(s) -
Han-Yao Huang,
Lawrence J. Appel,
Kevin D. Croft,
Edgar R. Miller,
Trevor A. Mori,
Ian B. Puddey
Publication year - 2002
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.1093/ajcn/76.3.549
Subject(s) - lipid peroxidation , malondialdehyde , oxygen radical absorbance capacity , vitamin e , vitamin c , vitamin , endocrinology , medicine , chemistry , antioxidant , ascorbic acid , biochemistry , food science , antioxidant capacity
Lipid peroxidation may be important in the pathogenesis of atherosclerosis, particularly in its earliest stages. Evidence predominantly from in vitro studies suggests that antioxidant vitamins can prevent lipid peroxidation and that vitamin C and vitamin E have synergistic effects. However, in vivo evidence in support of these hypotheses is sparse.

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