Antioxidant and thyroid hormone status in selenium-deficient phenylketonuric and hyperphenylalaninemic patients | Zendy

Marit ME van Bakel | Zendy; Gert Printzen | Zendy; Bendicht Wermuth | Zendy; Ulrich Wiesmann | Zendy

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Antioxidant and thyroid hormone status in selenium-deficient phenylketonuric and hyperphenylalaninemic patients

Author(s) -

Marit ME van Bakel,

Gert Printzen,

Bendicht Wermuth,

Ulrich Wiesmann

Publication year - 2000

Publication title -

american journal of clinical nutrition

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.608

H-Index - 336

eISSN - 1938-3207

pISSN - 0002-9165

DOI - 10.1093/ajcn/72.4.976

Subject(s) - glutathione peroxidase , medicine , endocrinology , selenium , antioxidant , selenium deficiency , hormone , triiodothyronine , chemistry , thyroid , uric acid , superoxide dismutase , biochemistry , organic chemistry

Subjects consuming protein-restricted diets, such as patients with phenylketonuria (PKU) or milder hyperphenylalaninemias (HPAs) are at risk of selenium deficiency. Selenium is a cofactor of the antioxidant enzyme glutathione peroxidase and of the thyroid hormone converting enzyme thyroxine deiodinase.

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