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Supplementation of postmenopausal women with fish oil rich in eicosapentaenoic acid and docosahexaenoic acid is not associated with greater in vivo lipid peroxidation compared with oils rich in oleate and linoleate as assessed by plasma malondialdehyde and F2-isoprostanes
Author(s) -
Jane V. Higdon,
Jiankang Liu,
Shi-Hua Du,
Jason D. Morrow,
Bruce N. Ames,
Rosemary C. Wander
Publication year - 2000
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.1093/ajcn/72.3.714
Subject(s) - fish oil , docosahexaenoic acid , eicosapentaenoic acid , tbars , polyunsaturated fatty acid , sunflower oil , food science , lipid peroxidation , chemistry , arachidonic acid , linoleic acid , fatty acid , biochemistry , biology , antioxidant , fish <actinopterygii> , enzyme , fishery
Although the replacement of dietary saturated fat with unsaturated fat has been advocated to reduce the risk of cardiovascular disease, diets high in polyunsaturated fatty acids (PUFAs) could increase lipid peroxidation, potentially contributing to the pathology of atherosclerosis.

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