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α-Tocopherol supplementation decreases production of superoxide and cytokines by leukocytes ex vivo in both normolipidemic and hypertriglyceridemic individuals
Author(s) -
Lambertus J. van Tits,
Pierre N.M. Demacker,
Jacqueline de Graaf,
Heidi L.M. Hak-Lemmers,
Anton F. H. Stalenhoef
Publication year - 2000
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.1093/ajcn/71.2.458
Subject(s) - superoxide , cytokine , endocrinology , medicine , zymosan , tocopherol , peripheral blood mononuclear cell , vitamin e , tumor necrosis factor alpha , immune system , chemistry , inflammation , immunology , antioxidant , biochemistry , in vitro , enzyme
alpha-Tocopherol plays an important role in protecting LDL against oxidation. However, additional effects of alpha-tocopherol at the intracellular level may contribute to the clinical outcome of intervention studies.

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