Open AccessPostprandial response of activated factor VII in elderly women depends on the R353Q polymorphism
Author(s) -
Louise Mennen,
Moniek PM de Maat,
Gert W. Meijer,
Peter L. Zock,
Diederick E. Grobbee,
Frans J. Kok,
Cornelis Kluft,
Evert G. Schouten
Publication year - 1999
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.1093/ajcn/70.4.435
Subject(s) - postprandial , genotype , medicine , allele , polymorphism (computer science) , crossover study , endocrinology , genotype frequency , allele frequency , biology , genetics , gene , alternative medicine , pathology , insulin , placebo
Activated factor VII (FVIIa) is a very potent coagulant and may be a key determinant of the outcome of a cardiovascular event. The main determinants of FVIIa are the R353Q polymorphism and dietary fat intake, which may have an interactive effect.
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