Vitamin K intake and hip fractures in women: a prospective study
Author(s) -
Diane Feskanich,
Peter Weber,
Walter C. Willett,
Helaine Rockett,
Sarah L. Booth,
Graham A. Colditz
Publication year - 1999
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.1093/ajcn/69.1.74
Subject(s) - medicine , hip fracture , vitamin d and neurology , prospective cohort study , osteoporosis , osteocalcin , relative risk , vitamin , physiology , bone density , cohort study , lower risk , endocrinology , bone mineral , confidence interval , biology , biochemistry , alkaline phosphatase , enzyme
Vitamin K mediates the gamma-carboxylation of glutamyl residues on several bone proteins, notably osteocalcin. High serum concentrations of undercarboxylated osteocalcin and low serum concentrations of vitamin K are associated with lower bone mineral density and increased risk of hip fracture. However, data are limited on the effects of dietary vitamin K.
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