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Choline supplemented as phosphatidylcholine decreases fasting and postmethionine-loading plasma homocysteine concentrations in healthy men
Author(s) -
Margreet R. Olthof,
Elizabeth J. Brink,
Mira Katan,
Petra Verhoef
Publication year - 2005
Publication title -
american journal of clinical nutrition
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.608
H-Index - 336
eISSN - 1938-3207
pISSN - 0002-9165
DOI - 10.1093/ajcn.82.1.111
Subject(s) - choline , phosphatidylcholine , plasma homocysteine , homocysteine , medicine , endocrinology , chemistry , phospholipid , biochemistry , membrane
A high homocysteine concentration is a potential risk factor for cardiovascular disease that can be reduced through betaine supplementation. Choline is the precursor for betaine, but the effects of choline supplementation on plasma total homocysteine (tHcy) concentrations in healthy humans are unknown.

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