Open AccessPlasma leptin levels are not predictive of dementia in patients with mild cognitive impairment
Author(s) -
R. Oania,
Linda K. McEvoy
Publication year - 2014
Publication title -
age and ageing
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.014
H-Index - 143
eISSN - 1468-2834
pISSN - 0002-0729
DOI - 10.1093/ageing/afu160
Subject(s) - leptin , dementia , medicine , biomarker , confounding , cohort , hazard ratio , cohort study , body mass index , endocrinology , cognitive decline , disease , obesity , confidence interval , biology , biochemistry
animal studies suggest a neuroprotective role for leptin, but human studies have shown mixed results. We examined whether plasma leptin levels in individuals with mild cognitive impairment (MCI) were related to cognitive function at baseline and whether higher leptin levels were associated with reduced risk of dementia.
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