Potential effect of skull thickening on the associations between cognition and brain atrophy in ageing | Zendy

Benjamin S. Aribisala | Zendy; Natalie A. Royle | Zendy; Maria C. Valdés Hernández | Zendy; Catherine Murray | Zendy; Lars Penke | Zendy; Alan J. Gow | Zendy; Susana Muñoz Maniega | Zendy; John M. Starr | Zendy; Mark E. Bastin | Zendy; Ian J. Deary | Zendy; Joanna M. Wardlaw | Zendy

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Potential effect of skull thickening on the associations between cognition and brain atrophy in ageing

Author(s) -

Benjamin S. Aribisala,

Natalie A. Royle,

Maria C. Valdés Hernández,

Catherine Murray,

Lars Penke,

Alan J. Gow,

Susana Muñoz Maniega,

John M. Starr,

Mark E. Bastin,

Ian J. Deary,

Joanna M. Wardlaw

Publication year - 2014

Publication title -

age and ageing

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.014

H-Index - 143

eISSN - 1468-2834

pISSN - 0002-0729

DOI - 10.1093/ageing/afu070

Subject(s) - brain size , atrophy , cognition , medicine , skull , thickening , neuroimaging , effects of sleep deprivation on cognitive performance , brain morphometry , cardiology , audiology , neuroscience , psychology , radiology , magnetic resonance imaging , anatomy , psychiatry , chemistry , polymer science

intracranial volume (ICV) is commonly used as a marker of premorbid brain size in neuroimaging studies as it is thought to remain fixed throughout adulthood. However, inner skull table thickening would encroach on ICV and could mask actual brain atrophy.

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