Association of chylothorax and direct pleura involvement in a case of Waldenstrom's macroglobulinaemia | Zendy

Johanne Poisson | Zendy; Amélie Arégui | Zendy; Luc Darnige | Zendy; Karin Maley | Zendy; Mathilde Gisselbrecht | Zendy

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Association of chylothorax and direct pleura involvement in a case of Waldenstrom's macroglobulinaemia

Author(s) -

Johanne Poisson,

Amélie Arégui,

Luc Darnige,

Karin Maley,

Mathilde Gisselbrecht

Publication year - 2014

Publication title -

age and ageing

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.014

H-Index - 143

eISSN - 1468-2834

pISSN - 0002-0729

DOI - 10.1093/ageing/afu061

Subject(s) - chylothorax , medicine , thoracic duct , waldenstrom macroglobulinemia , chemotherapy , infiltration (hvac) , lymphoma , pathology , lymphatic system , physics , thermodynamics

An 82-year-old male was hospitalised for dyspnoea, hypoxaemia and general fatigue; a predominant left chylothorax was revealed. Previously, he had been diagnosed with Waldenström's macroglobulinaemia (WM). Chylothorax complications in patients with WM are rare events and only six such cases have so far been reported. The most common malignant causes of chylothorax are through mediastinal adenopathy. Direct infiltration of the pleura by tumour cells is the most likely cause with this patient, and for this reason, we believe that this case is an instructive one. Chemotherapy induced rapid and persistent improvement after 10-month follow-up.

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