Superficial siderosis of the central nervous system: a rare cause of dementia with therapeutic consequences | Zendy

AnneLaure Dubessy | Zendy; Rénata Ursu | Zendy; Didier Maillet | Zendy; A. Augier | Zendy; J. Le Guilloux | Zendy; Alain Carpentier | Zendy; Cathérine Belin | Zendy

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Superficial siderosis of the central nervous system: a rare cause of dementia with therapeutic consequences

Author(s) -

AnneLaure Dubessy,

Rénata Ursu,

Didier Maillet,

A. Augier,

J. Le Guilloux,

Alain Carpentier,

Cathérine Belin

Publication year - 2012

Publication title -

age and ageing

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.014

H-Index - 143

eISSN - 1468-2834

pISSN - 0002-0729

DOI - 10.1093/ageing/afr177

Subject(s) - medicine , superficial siderosis , dementia , siderosis , ataxia , aspirin , etiology , central nervous system , cerebral amyloid angiopathy , neurological examination , pediatrics , pathology , disease , surgery , psychiatry

A 75-year-old patient was evaluated for dementia. His past medical history included an ischaemic cardiomyopathy treated with aspirin daily. His neurological examination showed mild ataxia syndrome and central deafness. The neuropsychological examination did not suggest Alzheimer's disease. No specific aetiology was found from biological investigations, but MRI scans revealed a superficial siderosis, which was further confirmed with CSF exams. This case highlights the interest of MRI with echo-gradient-T2 weighted sequences in patients investigated for memory disorders. Once the diagnosis is known, specific preventive measures have to be taken: searching for a treatable source of bleeding and the interruption of antiplatelet aggregation or anticoagulant treatments.

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