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o u r c e : h t t p s : / / d o i . o r g / 1 0 . 7 8 9 2 / b o r i s . 8 0 1 7 | d o w n l o a d e d : 4 . 7 . 2 0 2 1 glucose lowering in type 2 diabetes. N Engl J Med 2008; 358: 2545–59. 27. Bathum L, Christiansen L, Jeune B, Vaupel J, McGue M, Christensen K. Apolipoprotein e genotypes: relationship to cognitive functioning, cognitive decline, and survival in nonagenarians. J Am Geriatr Soc 2006; 54: 654–8. 28. Bergman A, Atzmon G, Ye K, MacCarthy T, Barzilai N. Buffering mechanisms in aging: a systems approach toward uncovering the genetic component of aging. PLoS Comput Biol 2007; 3: e170. 29. Silverman JM, Smith CJ, Marin DB et al. Identifying families with likely genetic protective factors against Alzheimer disease. Am J Hum Genet 1999; 64: 832–8. 30. Silverman JM, Schnaider-Beeri M, Grossman HT, Schmeidler J, Wang JY, Lally RC. A phenotype for genetic studies of successful cognitive aging. Am J Med Genet B Neuropsyciatr Genet 2008; 147B: 167–73.

age and ageing

Feasibility of repeated use of the Health Risk Appraisal for Older people system as a health promotion tool in community-dwelling older people: retrospective cohort study 2001-05