Testing homocysteine-induced neurotransmitter deficiency, and depression of mood hypothesis in clinical practice | Zendy

Salah Gariballa | Zendy

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Testing homocysteine-induced neurotransmitter deficiency, and depression of mood hypothesis in clinical practice

Author(s) -

Salah Gariballa

Publication year - 2011

Publication title -

age and ageing

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.014

H-Index - 143

eISSN - 1468-2834

pISSN - 0002-0729

DOI - 10.1093/ageing/afr086

Subject(s) - medicine , placebo , depression (economics) , quartile , mood , homocysteine , mood disorders , psychiatry , anxiety , confidence interval , pathology , economics , macroeconomics , alternative medicine

high total plasma homocysteine (tHcy) levels may cause neurotransmitter deficiency, and consequently depression of mood. We have recently shown that mixed oral nutritional supplements containing B-group vitamins led to a statistically significant benefit on depressive symptoms. The aim of this report was to examine the association between elevated plasma tHcy and symptoms of depression in older patients.

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