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Non-invasive ventilation in elderly patients with acute hypercapnic respiratory failure: a randomised controlled trial
Author(s) -
Stefano Nava,
Mario Grassi,
Francesco Fanfulla,
G Domenighetti,
Annalisa Carlucci,
Andréas Perren,
Daniela Dell’Orso,
Michele Vitacca,
Piero Ceriana,
Zühal Karakurt,
Enrico Clini
Publication year - 2011
Publication title -
age and ageing
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.014
H-Index - 143
eISSN - 1468-2834
pISSN - 0002-0729
DOI - 10.1093/ageing/afr003
Subject(s) - medicine , randomized controlled trial , intubation , respiratory rate , odds ratio , intensive care unit , mechanical ventilation , anesthesia , respiratory failure , mortality rate , respiratory distress , ventilation (architecture) , blood pressure , heart rate , mechanical engineering , engineering
older patients usually receive less invasive and costly hospital care, even if they meet the criteria for Intensive Care Unit admission or have a 'do not intubate'(DNI) order. The aim of this randomised, controlled trial was to assess the effectiveness of non-invasive mechanical ventilation (NIV) versus the standard medical therapy (SMT) in reducing the need of intubation, improving survival and reducing respiratory distress in very old patients with acute hypercapnic respiratory failure (AHRF).

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