Intravenous thrombolysis in stroke patients of ≥80 versus  | Zendy

Stefan T. Engelter | Zendy; Leo H. Bonati | Zendy; Philippe Lyrer | Zendy

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Intravenous thrombolysis in stroke patients of ≥80 versus <80 years of age—a systematic review across cohort studies

Author(s) -

Stefan T. Engelter,

Leo H. Bonati,

Philippe Lyrer

Publication year - 2006

Publication title -

age and ageing

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.014

H-Index - 143

eISSN - 1468-2834

pISSN - 0002-0729

DOI - 10.1093/ageing/afl104

Subject(s) - medicine , thrombolysis , modified rankin scale , stroke (engine) , odds ratio , cohort , confidence interval , cohort study , meta analysis , surgery , pediatrics , ischemic stroke , myocardial infarction , ischemia , mechanical engineering , engineering

elderly stroke patients were excluded or underrepresented in the randomised controlled trials of intravenous thrombolysis with recombinant tissue plasminogen activator (rtPA) applied within 3 h. Cohort studies comparing intravenous rtPA in stroke patients of >/=80 versus <80 years of age were limited by small sample sizes and yielded conflicting results. Thus, we performed a systematic review across all such studies.

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