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Impaired cognitive performance in asymptomatic peripheral arterial disease: relation to C-reactive protein and D-dimer levels
Author(s) -
R. A. Mangiafico,
F Sarnataro,
Marco Mangiafico,
Carmelo Erio Fiore
Publication year - 2005
Publication title -
age and ageing
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.014
H-Index - 143
eISSN - 1468-2834
pISSN - 0002-0729
DOI - 10.1093/ageing/afi219
Subject(s) - medicine , asymptomatic , subclinical infection , cardiology , peripheral , neuropsychology , stroke (engine) , arterial disease , cognition , population , disease , d dimer , vascular disease , psychiatry , mechanical engineering , environmental health , engineering
asymptomatic peripheral arterial disease (APAD), a highly prevalent condition in the general older population, is associated with an increased risk of cerebrovascular events because of co-existing clinical or subclinical cerebral atherosclerosis. The purpose of this study was to investigate whether cognitive function is impaired in stroke- and transient ischaemic attack-free patients with APAD, and whether inflammatory and haemostatic markers are associated independently with neuropsychological performance.

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