Age and frailty are independently associated with increased COVID-19 mortality and increased care needs in survivors: results of an international multi-centre study | Zendy

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Open Access

Age and frailty are independently associated with increased COVID-19 mortality and increased care needs in survivors: results of an international multi-centre study

Author(s) -

Mustafa Alsahab,

Lucy Beishon,

Bryony Brown,

Elinor Burn,

Jennifer Burton,

Natalie Cox,

Melanie Dani,

Muhammed Elhadi,

Sarah Freshwater,

Victoria Gaunt,

Adam Gordon,

Marie Goujon,

Matthew Hale,

Terry Lynn Hughes,

Thomas Jackson,

Benjamin Jelley,

Asma Khan,

Heena Khiroya,

Rajni Lal,

Katy Madden,

Laura Magill,

Jane Masoli,

Tahir Masud,

Lauren McCluskey,

Natalie McNeela,

Awolkhier Mohammedseid-Nurhussien,

Hannah Moorey,

Mary Ní Lochlainn,

Krishnarajah Nirantharakumar,

Kelvin Okoth,

Christopher N Osuafor,

Katherine Patterson,

Grace M E Pearson,

Rita Perry,

Michala E. Pettitt,

Jennifer Pigott,

Thomas Pinkney,

Terence J. Quinn,

Abigail Reynolds,

Sarah Richardson,

Nik Sanyal,

Adam Seed,

Isobel Sleeman,

C. R. de Soó,

Claire J. Steves,

W. David Strain,

Joanne Taylor,

Kelli Torsney,

Carly Welch,

Daisy Wilson,

Miles D. Witham,

Hossam Aldein S Abd Elazeem,

Mohammed Abdelhafez,

Amir Abdelmalak,

Omar Ahmed Abdelwahab,

Osama Mohamed Ali Senussi Abdulhadi,

Olubayode Adewole,

Mohammed Ahmad,

Eltayeb A Ahmed,

Hazem A. Sayed Ahmed,

Islam Ahmed,

Mertcan Akçay,

Yeşim Akdeniz,

Emrah Akın,

Carolyn Akladious,

Francesco Alessandri,

Ali Ali,

Abdulmalek Aljafari,

Abdulmoiz Aljafari,

Mohammed AlSadawi,

Lobna Al-Sodani,

Fatih Altıntoprak,

Gitanjali Amaratungaz,

Jocelyn Amer,

Sylvia Amini,

Taha Amir,

C Anandarajah,

Rachael Anders,

Muhammed H Ansari,

Kingsley Opoku Appiah,

Jolene Atia,

Catherine Atkin,

Avinash Aujayeb,

Elsayed M Awad,

Mohammed A. Azab,

Mohammad T. Azam,

Sally Aziz,

Ahmed Y. Azzam,

Laxmi Babar,

Laura Babb,

Manpreet Badh,

C L Baguneid,

Emily J Bailey,

Efstratia Baili,

Sarah Baldwin,

I Baloyiannis,

Moulinath Bannerjee,

Anna Barnard,

Fabio Barra,

Hannah Bashir,

Monica Bawor,

Zülfü Bayhan,

James Belcher,

Ravindra B Belgamwar,

Corrina Bentley,

Amy Birchenough,

Yen Nee J Bo,

Hayley R Boden,

Ahmad Bouhuwaish,

Gioia Brachini,

Laura Bremner,

Hannah Bridgwater,

Catherine Bryant,

Gabrielle Budd,

Sharon Budd,

Adam Budzikoski,

Reem Bulla,

Antonio Buondonno,

Nicole Burden,

Hejab Butt,

Recayi Çapoğlu,

Andra Caracostea,

R Carrillo Cardoso,

Alexis Carr,

M Carrasco Prats,

Caterina Cattel,

Giancarlo Ceccarelli,

Giuseppe Cecere,

Alexandros Charalabopoulos,

Evelyn Charsley,

Hannah Cheney-Lowe,

Theodore Chevallier,

Asad Choudhry,

Flavia Ciccarone,

Pierfranco Maria Cicerchia,

Bruno Cirillo,

Fatma D Collins,

Victoria Comerford,

Ahmed Cordie,

Siobhan Coulter,

Nick Coulthard,

Catrin Cox,

Victoria Cox,

Andrew Crowe,

Jack Cullen,

Jean Cummings,

Niamh Cunningham,

Daniel Curley,

Hannah Currie,

Madeleine Daly,

Jay Darley,

Nikhita Dattani,

Spyridon Davakis,

Rowan Davies,

Gilda De Paola,

Giorgio De Toma,

Sergio Del Valle-Ruiz,

Benyamin Deldar,

Hakan Demir,

Arjun Desai,

Nirali Desai,

Alice Devaney,

Lindsey Dew,

Jugdeep Dhesi,

Margarida Figueiredo-Dias,

Gordon Dick,

Parveen Doddamani,

Gurinder Dogra,

Tina Doll,

Hannah C. Dooley,

Samiullah Dost,

Catherine Dotchin,

Hannah Dowell,

Ioan M Draghita,

James Dundas,

Giulia Duranti,

Hiren Dusara,

Rajesh Dwivedi,

Adam H. Dyer,

Alison Eastaugh,

Elinor Edwards,

S M.elghazaly,

Ahmed O. Elmehrath,

Hope Elrick,

Mostafa Elshazly,

Alexander Emery,

Eric Etchill,

Sarah Evans,

Felicity Evison,

Cassandra Fairhead,

Margherita Faulkner,

Agnieszka Felska,

Antia Fernandez,

Pedro Vicente Fernández-Fernández,

Antonella Ferraiolo,

Simone Ferrero,

Enrico Fiori,

Necattin Fırat,

Gracie Fisk,

Anna Fleck,

Giovanni Battista Fonsi,

Alodia GabreKidan,

Gaetano Gallo,

Ratnam Gandhi,

Madeleine Garner,

Nikolaos Georgiou,

Hannah Gerretsen,

Nourhan A A Ghannam,

Andrew Ghobrial,

Hedra Ghobrial,

Zaynub Ghufoor,

Jake Ryan Gibbon,

Georgia F Gilbert,

M Giles,

Clara Giménez-Francés,

Emre Gönüllü,

Amy Gray,

Joshua H Gray,

Deirdre Green,

Charlotte Greene,

Ellanna Griffin,

Karla Griffith,

Anthony Grubb,

Yue Guan,

Daniel N Guerero,

Ayushi Gupta,

Claudio Gustavino,

Laurenny Guzman,

Ahmed Khalifa Hadreiez,

Jiannis Hajiioannou,

Deevia Hanji,

Deepthy Hari Madhavan,

Ahmet Tarık HARMANTEPE,

Patrick T. Harrison,

Barbara Hart,

Aidan Haslam,

Victoria J. Haunton,

Elliott R. Haut,

Torben Heinsohn,

Lindsay Hennah,

‏Helal F. Hetta,

Alexander Hickman,

Abigail Hobill,

Patrick Hogan,

Vesna Hogan,

Elizabeth A. Holmes,

K Honney,

Katharine Hood,

K. Hopkinson,

Lara Howells,

Nicole Hrouda,

Danielle Hunsley,

W. Jeffrey Hurst,

Rand A Hussein,

Mohamed Ibrahim,

Ishmam Ibtida,

Aina Ibukunoluwakitan,

Irem Ishlek,

Rishi Iyer,

Karl Jackson,

Rosie Jackson,

Ellen James,

Hayley Jarvis,

Sophie Jeffs,

Nathan Jenko,

Sasha Jeyakumar,

Shahriar Mahmud Kabir,

Harjinder Kainth,

Jason Kalloo,

Akhil Kanzaria,

Αmalia Karapanou,

Nuha Kardaman,

Sandeep Karthikeyan,

Anne Karunatilleke,

Mairéad Kelly,

Nicola Kelly,

Khalid Hesham,

Haris Khan,

Muhammad Shoaib Khan,

Matthew King,

Thomas Kneen,

Li Teng Kok,

Chiara Kratochwila,

Aneliya Kuzeva,

Pierfrancesco Lapolla,

Rebecca Lau,

Kar Yee Law,

A. J. Leadbetter,

Gabriel Lee,

Helena Lee,

Gavriella Levinson,

Emma Grace Lewis,

Theodore Liakakos,

Stephen Lim,

Danielle Lis,

Emma Livesey,

Pedro López-Morales,

Lily Lowes,

Eleanor Lunt,

Emily Lyon,

Suvira Madan,

Zeinab Majid,

Harsha Malapati,

Jade Man,

Baguiasri Mandane,

S Manning,

Barış Mantoğlu,

Nuria Martínez-Sanz,

William Marx,

Almontacer E B Masood,

Tom Maughan,

Jamie A Mawhinney,

Dominic Maxfield,

Jordan Mayer,

Henry Maynard,

Timothy J. McDonald,

Aine McGovern,

Sophie Mclachlan,

E Medina-Manuel,

Simona Meneghini,

Michelle Metcalf,

John Millwood-Hargrave,

Andrea Mingoli,

K. Miu,

Fawsiya Mohamed,

Soha M Mohamed,

Aliaë Mohamed-Hussein,

Abdulkader Mohammad,

Aaliya Mohammed,

Ahmed Abdulhakim Momen,

Farhana Moomo,

Ismael MoraGuzmán,

Lizzie Moriarty,

Hamilton Morrin,

Claire Morris,

Nicholas Moss,

Mohamed Moustafa,

Maria Mpoura,

Mohammed Mubin,

Ali Muhtaroğlu,

Georgina Muir,

Stephanie Mulhern,

David W.M. Muller,

Declan C. Murphy,

Bushra Muzammil,

Varun Nadkarni,

Mariam Albatoul Nageh,

Yasmin K. NasrEldin,

Wasim Nawaz,

Hanguyen,

Clíoí Cheallaigh,

Alexander P. Noar,

Samuel North,

Favour Nwolu,

Alice O’Docherty,

Omoteniola Similoluwa Odutola,

Sinead O’Dwyer,

Olebu Ogochukwu,

Catherine O’Mahony,

Lia Orlando,

Marc F. Österdahl,

Christina Page,

Ismini Panayotidis,

Shivam Pancholi,

Jessica Parkin,

Lauren Passby,

Patricia Pastor-Pérez,

Harnish P. Patel,

Shefali Patel,

Rose Penfold,

Rupini Perinpanathan,

Konstantinos Perivoliotis,

Teresa Perra,

Martha Pinkney,

Enrico Pinotti,

Alberto Porcu,

Angeline Price,

Francesco Pugliese,

Prabhleen Puri,

Sylvia Pytraczyk,

Yusra Qaiser,

Maria Qurashi,

Dina Radenković,

Thurkka Rajeswaran,

Sarah Rapaport,

Tahmina Razzak,

Lara Reilly,

Paul N. Reynolds,

Alexandra Richardson,

Amelia Roberts,

Charlotte Roberts-Rhodes,

Tanya O. Robinson,

Aldo Rocca,

Emily Ross-Skinner,

Miguel RuizMarín,

Rebecca Ryall,

Alshaimaa M Saad,

Mahmoud Saad,

Ambreen Sadiq,

Giuseppe Sammarco,

Michail A Sampanis,

Hazel Sanghvi,

Paolo Sapienza,

R. R. Sayers,

Luca Scott,

Michael Sen,

Mosab Abdelrazak A. Shaban,

Kathleen T Shakespeare,

Ellie Shaw,

Hannah Shaw,

Jonathan Sheldrake,

Sing Yang Sim,

L Simonelli,

Nikolaos V. Sipsas,

Jarita Sivam,

Sri Sivarajan,

Jennifer J. Smith,

F Speranza,

Claire Spice,

Amanda Stafford,

Katharine Stambollouian,

Kent A. Stevens,

Jack Stewart,

Emma Stratton,

Hannah Street,

Michael Surtees,

Emma Swinnerton,

Ahmed S A Taher,

Caroline Tait,

Amybel Taylor,

Miriam Thake,

Katie Thin,

Hannah Thould,

Thyn Thyn,

Benjaman To,

Hannah Tobiss,

Kathryn Toppley,

Liam Townsend,

Ellen Tullo,

George Tzovaras,

Anthony Umeadi,

Hrisheekesh J Vaidya,

María Valero-Soriano,

Rosanna Varden,

Vittoria Vergani,

Dominique Vervoort,

Giuseppina Vescio,

M Vettasseri,

Madiha Virk,

Vaishali Vyas,

Joanne Wagland,

Stephanie Wallis,

Chloe Warner,

Eleanor Watkins,

Hannah Watson,

Rachael Webb,

Sarah Welsh,

Ruth West,

Elisha Whelan,

Julie Whitney,

Mark Whitsey,

Catherine Wilcock,

Iain D. Wilkinson,

David Williams,

Megan Williamson,

Ruth Willott,

Mettha Wimalasundera,

Yu Lelt Win,

Laura Winter,

Stephanie Worrall,

Rebecca Wright,

Natalie Yeo,

Eirene Yeung,

Merve Yiğit,

Yasin Alper Yıldız,

Humza Yusuf,

Martina Zambon,

Hein Zaw,

Omar Zein Elabedeen

Publication year - 2021

Publication title -

age and ageing

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.014

H-Index - 143

eISSN - 1468-2834

pISSN - 0002-0729

DOI - 10.1093/ageing/afab026

Subject(s) - medicine , hazard ratio , interquartile range , delirium , proportional hazards model , odds ratio , dementia , confidence interval , disease , intensive care medicine

Increased mortality has been demonstrated in older adults with coronavirus disease 2019 (COVID-19), but the effect of frailty has been unclear.

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